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Wednesday, May 31, 2017

Domoic Acid -- Only Partly Responsible For Mass Pacific Die-Offs, Here Is The Whole Story

Summary by stock -- a commentor at ENENEWS who goes by "CodeShutdown" provided much of the information and got me going down this path.
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The below resources list is mostly a jumble of sources that I gathered together in the process of wrapping my head around the mass ocean deaths in the Pacific.

In 2016 we busted NOAA and MSM dead to rights lying about all the deaths, throwing out "Domoic Acid" as the main culprit even though when I got my hands on their real data, it only showed 1 to 3% deaths caused by Domoic Acid.

Starvation and a weakened immune system were the main culprits, as they are now.

So we know that krill are highly affected by even low levels of radiation in the environment, proven by test data on the CS134/CS137 ratio in water showing that the krill are taking CS134 to Davy Jone locker at faster rates because it kills them faster.

The disappearance of krill also allows other phytoplankton to expand.    More algae.   More Domoic Acid.    Domoic Acid latches on to Brain Neurons and causes them to fire.   But here is the real kicker, Domoic Acid acts like a chelator and can grab and carry heavy metals with it. 

So any radioisotopes present can be neatly delivered right right to the brain neurons, for a wicked double whammy. 

Additionally, we know that even low levels of radiation bio-magnify in Chitin, a biological structure of great importance in many ocean flora and fauna.    Radiation is one of the few things that can break the tough Chitin bonds, so it can blow up the structure of animals and plants.   But its destruction does not have to end just there.   It can also, when close to DNA, destroy that DNA.  

But it gets even "better", Chitin is also used in cell walls, where it affects  the ionic and voltage gradients which are prime mechanisms that allow and tell cells how to function, change, grow.    Morphogenesis -- is the fancy way of describing how cells grow into different body parts, and so it should be obvious that having damaged Chitin in the cells is not going to be a good thing for proper cellular development.

But if you ask the "scientists" at the International Atomic Energy Association, they will explain that radiation damage can be 100% calculated by modelling the human body literally as a bag of water with energy being deposited into it.    It is shameful.

So to sum it up:
  1. Radiation destroys chitin structure, DNA, and cell growth and bio-magnifies
  2. This causes a huge amount of the food chain to simply sink to the bottom
  3. Radiation also damages the immune system  in a number of ways, particularly gut flora (70% of the immune system created in the gut) and creating hurtful immune response.
  4. Radiation allows more algae, and thus Domoic Acid, to be created
  5. Domoic acid grabs radiation and then delivers itself and the radiation directly to the brain and nervous system of sea critters, making them confused, lethargic.
  6. So the food chain is massively hurt, the critters are sick and can't think well, therefore they can't even hunt well for the available food.
  7. And we have what we are seeing in the real world.

But the military/fed funded scientists who are directed to make sure that people are smiling and unaware of the causes of the mass die-offs:
1) Test the water only, and state how there is no danger
2) Hang their hats on the ICRP radiation danger dose model (just a bag of water)


 CodeShutdown

Domoic acid is a heavy metal transporter used by those toxic plankton to modulate different metals to their needs…iron, copper… There is an analogy; Some molds thrive in radioactive environments…they live off it. They use melanin, and the mold is black with it.

So anyway its a possibility, just a hypothesis, that the nuclear toxins are better handled by the toxic algae because of the domoic acid, which gives them an edge in the competitive world.

The domoic acid may bioconcentrate radionuclides also, and I wonder if it is shuttled to the nervous system. As an analog of glutamate, an excitatory neurotransmitter,

DA binds to the kainate type of glutamate receptors, but with a binding capacity three times greater and 20 times more powerful than kainic acid

run with it stock…call it a discovery
per code
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Chitin is a polysaccharide biological structural polymer found in exoskeletons, like insects, crabs, beaks of squid etc, and combined with calcium carbonate to form shells of crustaceans. It absorbs radioactive fallout.

"radiation destruction of chitin
The change in functional composition and molecular mass of crab, shrimp, and Antarctic shrimp (krill) chitin under the effect of ionizing radiation has been studied….it was established that primary radicals appear in positions 1 and 4 of the pyranose ring with subsequent breakdown of the glycoside bond analogous to cellulose and chitosan decay when ╬│-irradiated."
https://inis.iaea.org/search/search.aspx?orig_q=RN:26023735


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Kainic acid (kainate) is a natural marine acid present in some seaweed.

Kainic acid is a potent neuroexcitatory amino acid agonist that acts by activating receptors for glutamate, the principal excitatory neurotransmitter in the central nervous system. Glutamate is produced by the cell’s metabolic processes and there are four major classifications of glutamate receptors: NMDA receptors, AMPA receptors, kainate receptors, and the metabotropic glutamate receptors.

Kainic acid is an agonist for kainate receptors, a type of ionotropic glutamate receptor. Kainate receptors likely control a sodium channel that produces excitatory postsynaptic potentials (EPSPs) when glutamate binds.[1]

Kainic acid is commonly injected into laboratory animal models to study the effects of experimental ablation. Kainic acid is a direct agonist of the glutamic kainate receptors and large doses of concentrated solutions produce immediate neuronal death by overstimulating neurons to death.

Such damage and death of neurons is referred to as an excitotoxic lesion. Thus, in large, concentrated doses kainic acid can be considered a neurotoxin, and in small doses of dilute solution kainic acid will chemically stimulate neurons.[2]

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Morphogenesis (from the Greek morphê shape and genesis creation, literally, "beginning of the shape") is the biological process that causes an organism to develop its shape. It is one of three fundamental aspects of developmental biology along with the control of cell growth and cellular differentiation, unified in evolutionary developmental biology (evo-devo).

The process controls the organized spatial distribution of cells during the embryonic development of an organism. Morphogenesis can take place also in a mature organism, in cell culture or inside tumor cell masses. Morphogenesis also describes the development of unicellular life forms that do not have an embryonic stage in their life cycle, or describes the evolution of a body structure within a taxonomic group.

Morphogenetic responses may be induced in organisms by hormones, by environmental chemicals ranging from substances produced by other organisms to toxic chemicals or radionuclides released as pollutants, and other plants, or by mechanical stresses induced by spatial patterning of the cells.

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cant wait until you realize the other part of the story stock. The chitin acts like an ion exchange resin…and the radiation CAN break down the chitin,
http://enenews.com/mass-death-species-found-around-fukushima-nuclear-plant-govt-disappeared-little-reproductive-success-evident-biota-around-power-plant-affected-nuclear-accident/comment-page-1#comment-746906
BUT there is a whole other path of influence. The chitin machinery is right there on the cell wall, and several things have been discovered which influence morphogenesis…which limb goes where…which microtubule in the cell cytoskeleton goes which way…among which influence is the ionic gradient and the voltage gradient.

So EVEN IF the chitin is not degraded significantly, or if its consumed by a non chitin based animal…it still forms a hot spot of ionic and voltage gradient which can interfere with morphogensis on the macro and micro scale.

Indeed, ion gradients and flow is a large factor in biochemical process and morphogenisis. Needless to say this is a deforming potential not directly related to DNA breaks.

In fact has been found that organisms can select for different isotopes; "it is thought that accumulation of radionuclide elements follows that of nonradioactive elements. However, with the
discovery of isotope discrimination for a number of elements by a range of organisms, this may not hold true.

You arent done with your discovery process

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Jebus
"a hot spot of ionic and voltage gradient"

This fits in there.

"Collectively these data demonstrate that low-dose ionizing radiation has an important effect on absorbing water, consuming O2 and releasing CO2, which means the risk for embryo and endosperm development was higher."

http://www.sciencedirect.com/science/article/pii/S0022519317302382

Embryogenesis comes to mind… -----------------------------------------------------------------
Code:
Might be a key as to how radiation directly damages immune system besides the gut based flora route that I have already established
http://mbio.asm.org/content/3/2/e00056-12.full
Besides the role of chitin in supporting structural stability, chitin and host enzymes with chitinase activity have an important role in host defense and modifying the inflammatory response. Thus, chitin appears to provide a link between the fungus and host that involves both innate and adaptive immune responses. Recently, there has been increased attention to the role of chitinases in the pathogenesis of allergic inflammation, especially asthma. We review these findings and explore the possible connection between fungal infections, the induction of chitinases, and asthma.


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So far, this seems restricted to fungal cell wall, and not cell walls in other chitin uses, but we shall see…..


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Localization of chitin in algal and fungal cell walls by light and electron microscopy.

Abstract

Chitin was visualized in cell walls after hydrolysis with potassium hydroxide and subsequent postfixation of the deacetylated polysaccharide (chitosan) in OsO4. Areas of chitin deposition appeared dark borwn by light microscopy and electron dense in the electron microscope. With this method, the presence of chitin was demonstrated in the cell walls of the green alga Pithophora oedogonia (Montagne) Wittrock and two fungi, Ceratocystis ulmi Buism. (C. Moreau) and Blastocladiella emersonii Cantino and Hyatt. Most of the chitin in P. oedogonia ws found in the crosswall disk and small amounts occurred in the outer longitudinal walls. The septal disk of C. ulmi also contained chitin, but significant amounts were present in the inner and outer regions of longitudinal walls as well. Chitin was present throughout the walls of B. emersonii. Small amounts of chitin were not easily demonstrated by this technique, but removal of chitosan by exposure to dilute acetic acid before osmium fixation disrupted cell wall integrity, suggesting that small amounts of the structural polysaccharide had been removed.---------------------------------------------------------------

http://www.mdpi.com/1660-3397/11/7/2398/htm

The low iron treatment may have increased the susceptibility of S. marinoi to other stressors, in this case, domoic acid. Previous studies have shown that nutrient limitation increases the susceptibility of phytoplankton to radiation [23,24] and to unidentified allelopathic compounds produced by other phytoplankton [25]. From this experiment, it is not clear whether domoic acid directly inhibits the growth of S. marinoi or if domoic acid binds iron, and reduces iron availability to the already iron limited S. marinoi cells

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HoTaters
Formation of excessive fibrinogen inside arteries and vessels is an inflammatory response to a toxin, or pathogen. There may be other causes. Kent Holtorff, M.D., discusses this in detail in a video at his website. He discusses it in the context of an inflammatory cascade and the long-term development of chronic disease states.
'Ho out ….

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Code say---
The cell wall of candida is composed of fibrin and chitin. I sometimes think of humans as a kind of out of control fungal growth…but regardless…we always have some chitin going in…we eat it, colonized by it. Especially oceanic mammals. But I was going to mention the fibrin…its in the back of my mind to research this because Ive noticed more people getting thrombosis and there are some similarities of fibrin and chitin

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Code emailed in

for what its worth....the fallout is absorbed and travels with the MSG, and thus most assuredly with the glutamine and domoic acid,  binds to the glutamine receptors and lingers there.  The glutamine is heavily tied to mitochondria health, cancer progression, vascular inflammation, thrombosis, and on.  The key story is that science believes without question that radiation = radiation. But we know that both specific activity and the largely unexplored frequency and harmonics, as well as the chemical nature of the isotope all differentiate man made radiation
from so called background.   This is the hurdle...convincing young
scientists that nuclear fallout is different, worse, of unknown biological cascade effect, promotes morbidity, not just all or nothing hit or miss cancer, bioaccumulates in known and unknown ways and causes hot spots on macro and micro scales

Selective distribution of radioactivity in the neonatal mouse brain following subcutaneous administration of 14C-labeled monosodium glutamate
  Radioactivity and its distribution in the neonatal mouse brain following subcutaneous administration of 14C-labeled monosodium glutamate (MSG) were studied by means of radiometry and freezing autoradiography. The brain level of radioactivity proportionally increased and peaked at 3 hours after the injection of radiolabeled MSG, then gradually decreased, whereas the blood level of radioactivity rapidly increased, peaking at 50 minutes, and rapidly decreased therafter. The radioactivity on the brain autoradiograph was less than in other head tissues, but marked accumulation of radioactivity was observed in the retina, lens, preoptic area, hippocampus, dorsal surface of thalamus, arcuate nuclear region, and choroid plexus of lateral and third ventricles at 15 minutes to 24 hours. These areas, except lens and choroid plexus, correspond to the sites of MSG-induced lesions.



 

2 comments:

  1. If WHOI were worth their weight they'd be researching this line of inquiry. Instead they haul buckets of water to the lab and check a few fish ...

    ReplyDelete
  2. Whilst a few people, working for free, probably in their basement,figure out the basis of the death of the Pacific

    It is shameful methinks

    ReplyDelete

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